Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.62 |
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.47 |
| ▸ | NAMPT | P43490 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23867964 | 1.00 | MGLL (0.62) | MGLLGPR119NAMPTALDH1A1PDE4A | |
| SCHEMBL23868042 | 0.89 | MGLL (0.61) | MGLLGPR119NAMPTPDE4APDE4B | |
| SCHEMBL30104745 | 0.89 | MGLL (0.61) | MGLLGPR119NAMPTPDE4APDE4B | |
| SCHEMBL30104720 | 0.85 | MGLL (0.59) | MGLLGPR119NAMPT | |
| SCHEMBL23867968 | 0.85 | MGLL (0.59) | MGLLGPR119NAMPT | |
| SCHEMBL23867886 | 0.83 | MGLL (0.58) | MGLLGPR119NAMPTSMN1; SMN2 | |
| SCHEMBL30104728 | 0.83 | MGLL (0.58) | MGLLGPR119NAMPTSMN1; SMN2 | |
| SCHEMBL23867903 | 0.80 | MGLL (0.64) | MGLLALDH1A1HSD17B10HTTSMN1; SMN2 | |
| SCHEMBL24350749 | 0.80 | MGLL (0.58) | MGLLGPR119ALDH1A1HSD17B10HTT | |
| SCHEMBL23859675 | 0.79 | MGLL (0.77) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115362153-A | Aza spiro rings as monoacylglycerol lipase modulators | 詹森药业有限公司 | 2022-11-18 | — | — | CN | disclosed |