SCHEMBL30104745 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	MGLL	Q99685	5/20	0.61

▸	GPR119	Q8TDV5	5/20	0.44

▸	PDE4B	Q07343	4/20	0.43

▸	PDE4A	P27815	2/20	0.43

▸	PDE4C	Q08493	2/20	0.43

▸	PDE4D	Q08499	2/20	0.43

▸	STS	P08842	1/20	0.42

▸	MEN1	O00255	2/20	0.41

▸	KMT2A	Q03164	2/20	0.41

▸	NAMPT	P43490	3/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL23868042	1.00	MGLL (0.61)	MGLLGPR119PDE4BPDE4APDE4C
SCHEMBL23867964	0.89	MGLL (0.62)	MGLLGPR119PDE4BPDE4APDE4C
SCHEMBL30104729	0.89	MGLL (0.62)	MGLLGPR119PDE4BPDE4APDE4C
SCHEMBL30104720	0.88	MGLL (0.59)	MGLLGPR119NAMPT
SCHEMBL23867968	0.88	MGLL (0.59)	MGLLGPR119NAMPT
SCHEMBL23867886	0.86	MGLL (0.58)	MGLLGPR119NAMPT
SCHEMBL30104728	0.86	MGLL (0.58)	MGLLGPR119NAMPT
SCHEMBL23867916	0.84	MGLL (0.55)	MGLLGPR119MEN1KMT2ANAMPT
SCHEMBL23868000	0.79	MGLL (0.59)	MGLLGPR119NAMPT
SCHEMBL29426996	0.79	MGLL (0.59)	MGLLGPR119NAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-115362153-A	Aza spiro rings as monoacylglycerol lipase modulators	詹森药业有限公司	2022-11-18	—	—	CN	disclosed