Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 2/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.43 |
| ▸ | MGLL | Q99685 | 4/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | NOTCH1 | P46531 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31388902 | 0.91 | NOTCH1 (0.48) | STSGPR119TGFBR1NOTCH1TACR1 | |
| SCHEMBL31388961 | 0.88 | GPR119 (0.55) | STSGPR119PTPN2PTPN1PTPN6 | |
| SCHEMBL31388886 | 0.86 | GPR119 (0.41) | STSGPR119MGLLTGFBR1NAMPT | |
| SCHEMBL31388949 | 0.83 | GPR119 (0.42) | GPR119MGLLPTPN2PTPN1PTPN6 | |
| SCHEMBL31388924 | 0.83 | MGLL (0.47) | STSGPR119MGLLTACR1KDM1A | |
| SCHEMBL23868000 | 0.81 | MGLL (0.59) | GPR119MGLLNAMPT | |
| SCHEMBL29426996 | 0.81 | MGLL (0.59) | GPR119MGLLNAMPT | |
| SCHEMBL31388944 | 0.80 | GPR119 (0.54) | GPR119PTPN2PTPN1PTPN6NAMPT | |
| SCHEMBL31388969 | 0.77 | GPR119 (0.50) | GPR119NAMPT | |
| SCHEMBL31388913 | 0.77 | IDH1 (0.44) | STSGPR119MGLLNAMPTKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115362153-B | Azaspiro compounds as monoacylglycerol lipase modulators | 詹森药业有限公司 | 2025-01-07 | — | — | CN | disclosed |
| CN-115362153-A | Aza spiro rings as monoacylglycerol lipase modulators | 詹森药业有限公司 | 2022-11-18 | — | — | CN | disclosed |