Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.42 |
| ▸ | ACACB | O00763 | 6/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31388918 | 0.88 | GPR119 (0.49) | GPR119ACACBKMT2ANAMPTMEN1 | |
| SCHEMBL30104735 | 0.83 | STS (0.44) | GPR119NAMPTMGLLPTPN2PTPN1 | |
| SCHEMBL31388969 | 0.83 | GPR119 (0.50) | GPR119ACACBKMT2ANAMPTMEN1 | |
| SCHEMBL23867968 | 0.82 | MGLL (0.59) | GPR119ACACBNAMPTMGLL | |
| SCHEMBL30104720 | 0.82 | MGLL (0.59) | GPR119ACACBNAMPTMGLL | |
| SCHEMBL31388944 | 0.79 | GPR119 (0.54) | GPR119KMT2ANAMPTPTPN2PTPN1 | |
| SCHEMBL31388961 | 0.77 | GPR119 (0.55) | GPR119KMT2ANAMPTMEN1PTPN2 | |
| SCHEMBL31388941 | 0.76 | GPR119 (0.46) | GPR119KMT2AMEN1KDM4E | |
| SCHEMBL23867886 | 0.76 | MGLL (0.58) | GPR119NAMPTMGLL | |
| SCHEMBL30104728 | 0.76 | MGLL (0.58) | GPR119NAMPTMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115362153-B | Azaspiro compounds as monoacylglycerol lipase modulators | 詹森药业有限公司 | 2025-01-07 | — | — | CN | disclosed |