Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL525172 | 1.00 | ALDH1A1 (0.41) | ALDH1A1TSHRHSD17B10LMNATDP1 | |
| SCHEMBL7160702 | 0.81 | ALDH1A1 (0.41) | ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL7160703 | 0.81 | ALDH1A1 (0.41) | ALDH1A1TSHRHSD17B10TDP1 | |
| SCHEMBL9928633 | 0.80 | ALDH1A1 (0.36) | ALDH1A1TSHRHSD17B10LMNATDP1 | |
| SCHEMBL9928634 | 0.80 | ALDH1A1 (0.36) | ALDH1A1TSHRHSD17B10LMNATDP1 | |
| SCHEMBL531366 | 0.77 | — | — | |
| SCHEMBL531365 | 0.77 | — | — | |
| SCHEMBL10336145 | 0.75 | — | — | |
| SCHEMBL6671546 | 0.72 | — | — | |
| SCHEMBL2397840 | 0.72 | ALDH1A1 (0.47) | ALDH1A1TSHRHSD17B10LMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100196287-A1 | Compositions Comprising Perhydrolases and Alkylene Glycol Diacetates | HENKEL AG & CO. KGAA (DE) | 2010-08-05 | — | — | US | disclosed |
| US-6559347-B2 | As dienophiles with dienes such as cyclopentadiene and cyclohexadiene, at an elevated pressure | WAKE FOREST UNIVERSITY HEALTH SCIENCES | 2003-05-06 | — | — | US | disclosed |
| US-20020173668-A1 | Diels-alder adducts of epoxybutene and epoxybutene derivatives | WAKE FOREST UNIVERSITY | 2002-11-21 | — | — | US | disclosed |
| US-6380447-B1 | PRESSURIZATION; FORMING BICYCLIC COMPOUNDS | WAKE FOREST UNIVERSITY | 2002-04-30 | — | — | US | disclosed |
| US-4661646-A | Process for the preparation of 1-butene-3,4-diol | BAYER AKTIENGESELLSCHAFT (DE) | 1987-04-28 | — | — | US | disclosed |
| US-4238356-A | REACTION PRODUCT OF A CARBOXYLIC ACID, SELENIUM DIOXIDE, A HYDROXIDE OR ACID SALT, AND AN ACID ANHYDRIDE | PHILLIPS PETROLEUM COMPANY (US) | 1980-12-09 | — | — | US | disclosed |
| US-4182901-A | AND SUITABLE CARBOXYLIC ACID | PHILLIPS PETROLEUM COMPANY (US) | 1980-01-08 | — | — | US | disclosed |
| US-4164616-A | FROM THE CONJUGATED DIENE | PHILLIPS PETROLEUM COMPANY (US) | 1979-08-14 | — | — | US | disclosed |
| US-4121039-A | REACTING CONJUGATED DIENE WITH OXYGEN, CATALYST SELECTIVITY | GAF CORPORATION (US) | 1978-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020173668-A1 | Diels-alder adducts of epoxybutene and epoxybutene derivatives | DERA, CYP11B1, SQLE | ALDH1A1 19/4885TSHR 4885/4885HSD17B10 188/4885 |
| US-20100196287-A1 | Compositions Comprising Perhydrolases and Alkylene Glycol Diacetates | HDHD5, MGLL, DAGLA | ALDH1A1 286/4885TSHR 4089/4885HSD17B10 116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.