Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 12/20 | 0.49 |
| ▸ | HTR2A | P28223 | 10/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | AXL | P30530 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30104854 | 0.75 | HTR2C (0.49) | HTR2CHTR2AADRB2ADRB1HTR2B | |
| SCHEMBL30104796 | 0.74 | HTR2C (0.62) | HTR2CHTR2AADRB2ADRB1HTR2B | |
| SCHEMBL30104808 | 0.73 | RPS6KA2 (0.42) | ADRB1MEN1KMT2A | |
| SCHEMBL4705406 | 0.69 | HTR2A (0.68) | HTR2CHTR2AKCNH2 | |
| SCHEMBL3155248 | 0.69 | HTR2C (0.69) | HTR2CHTR2ASCN7AKCNH2SCN9A | |
| SCHEMBL27311351 | 0.67 | HTR2A (0.45) | HTR2CHTR2A | |
| SCHEMBL17986104 | 0.67 | MCHR1 (0.46) | HTR2CHTR2AMEN1KMT2AMCHR1 | |
| SCHEMBL2356686 | 0.66 | HTR2A (1.00) | HTR2CHTR2A | |
| SCHEMBL5917403 | 0.66 | HTR2A (0.68) | HTR2CHTR2A | |
| SCHEMBL5917499 | 0.66 | HTR2C (1.00) | HTR2CHTR2AADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396485-A | PARP7 inhibitors | 轩竹生物科技股份有限公司 | 2024-01-12 | — | — | CN | disclosed |
| WO-2022247839-A1 | PARP7 INHIBITOR | 山东轩竹医药科技有限公司 | 2022-12-01 | — | — | WO | disclosed |