Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA2 | Q15349 | 5/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.40 |
| ▸ | PARP1 | P09874 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.38 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30104810 | 0.76 | HRH3 (0.42) | RPS6KA2HRH3PARP1CYP2D6MAPKAPK2 | |
| SCHEMBL30104848 | 0.76 | HRH3 (0.49) | RPS6KA2HRH3PARP1CYP2D6MAPKAPK2 | |
| SCHEMBL29153647 | 0.76 | HRH3 (0.49) | RPS6KA2HRH3PARP1CYP2D6MAPKAPK2 | |
| SCHEMBL30954503 | 0.73 | PARP1 (0.44) | RPS6KA2HRH3PARP1CYP2D6MAPKAPK2 | |
| SCHEMBL27311284 | 0.73 | PARP1 (0.44) | RPS6KA2HRH3PARP1CYP2D6MAPKAPK2 | |
| SCHEMBL30104846 | 0.73 | HTR2C (0.49) | MEN1KMT2AADRB1 | |
| SCHEMBL19187485 | 0.71 | HRH3 (0.52) | RPS6KA2HRH3PARP1CYP2D6MAPKAPK2 | |
| SCHEMBL27312316 | 0.69 | RPS6KA3 (0.38) | RPS6KA2HRH3PARP1CYP2D6MAPKAPK2 | |
| SCHEMBL30172384 | 0.68 | RPS6KA3 (0.53) | RPS6KA2HRH3PARP1CYP2D6MAPKAPK2 | |
| SCHEMBL1393632 | 0.68 | RPS6KA3 (0.53) | RPS6KA2HRH3PARP1CYP2D6MAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396485-A | PARP7 inhibitors | 轩竹生物科技股份有限公司 | 2024-01-12 | — | — | CN | disclosed |
| WO-2022247839-A1 | PARP7 INHIBITOR | 山东轩竹医药科技有限公司 | 2022-12-01 | — | — | WO | disclosed |