Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 9/20 | 0.49 |
| ▸ | HTR2A | P28223 | 8/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.31 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.31 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30104846 | 0.75 | HTR2C (0.49) | HTR2CHTR2AADRB1ADRB2SCN9A | |
| SCHEMBL30104796 | 0.74 | HTR2C (0.62) | HTR2CHTR2AADRB1ADRB2HTR2B | |
| SCHEMBL3983638 | 0.74 | HTR2A (0.58) | HTR2CHTR2A | |
| SCHEMBL30104810 | 0.73 | HRH3 (0.42) | — | |
| SCHEMBL24640538 | 0.72 | HTR2C (0.42) | HTR2CHTR2AADRB1ADRB2SCN9A | |
| SCHEMBL4705406 | 0.69 | HTR2A (0.68) | HTR2CHTR2AKCNH2 | |
| SCHEMBL3155248 | 0.69 | HTR2C (0.69) | HTR2CHTR2ASCN9ASCN10AKCNH2 | |
| SCHEMBL411656 | 0.68 | HTR2A (0.36) | HTR2CHTR2AADRB1HTR2B | |
| Hydrochloric Acid SCHEMBL14956768 | 0.67 | HTR2A (0.35) | HTR2CHTR2AADRB1ADRB2HTR2B | |
| SCHEMBL5917457 | 0.67 | HTR2C (0.60) | HTR2CHTR2AADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396485-A | PARP7 inhibitors | 轩竹生物科技股份有限公司 | 2024-01-12 | — | — | CN | disclosed |
| WO-2022247839-A1 | PARP7 INHIBITOR | 山东轩竹医药科技有限公司 | 2022-12-01 | — | — | WO | disclosed |