Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.42 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.42 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4688032 | 0.85 | ALDH1A1 (0.49) | GAATRPV1ALDH1A1HPGDMAPT | |
| SCHEMBL7837046 | 0.84 | ALDH1A1 (0.61) | GAAKDM4ETRPV1ALDH1A1HPGD | |
| SCHEMBL2487614 | 0.83 | TRPV1 (0.40) | GAAKDM4ETRPV1ALDH1A1HPGD | |
| SCHEMBL29581095 | 0.83 | GRIN2D (0.49) | GAAKDM4EALDH1A1GRIN2DGRIN3B | |
| SCHEMBL5101721 | 0.83 | ALDH1A1 (0.53) | KDM4ETRPV1ALDH1A1HPGDPOLB | |
| SCHEMBL4521444 | 0.83 | L3MBTL1 (0.52) | GAAKDM4ETRPV1ALDH1A1HPGD | |
| SCHEMBL1953147 | 0.83 | GRIN2D (0.49) | GAAKDM4EALDH1A1GRIN2DGRIN3B | |
| SCHEMBL465541 | 0.82 | GAA (0.52) | GAAKDM4EALDH1A1HPGDGRIN2D | |
| SCHEMBL29840042 | 0.82 | GAA (0.52) | GAAKDM4EALDH1A1HPGDGRIN2D | |
| SCHEMBL7258705 | 0.82 | ALDH1A1 (0.42) | GAATRPV1ALDH1A1HPGDGRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121415-B1 | INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 1-[2-(HYDROXYALKYL)PHENYL]-3-YLUREA, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES | UNIV PALACKEHO (CZ) | 2024-02-07 | — | — | EP | disclosed |
| EP-4121415-A1 | INHIBITORS OF CYTOKININ OXIDASE DERIVED FROM 1-[2-(HYDROXYALKYL)PHENYL]-3-YLUREA, USE THEREOF AND PREPARATIONS CONTAINING THESE DERIVATIVES | Univerzita Palackého v Olomouci (CZ) | 2023-01-25 | — | — | EP | disclosed |