SCHEMBL3010602

SCHEMBL3010602

O=S(=O)(O)c1cc(O)c(N=Nc2c(O)ccc3ccccc23)c2ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MPL P40238 12/20 1.00
CTRC Q99895 2/20 1.00
NSD2 O96028 1/20 0.64
MMP14 P50281 1/20 0.64
CASP6 P55212 1/20 0.64
MAPT P10636 2/20 0.62
KMT2A Q03164 2/20 0.62
GAA P10253 1/20 0.62
MAPK1 P28482 1/20 0.62
TDP1 Q9NUW8 1/20 0.62
CYP1A2 P05177 2/20 0.62
CYP2C9 P11712 2/20 0.62
TSHR P16473 2/20 0.62
CYP2C19 P33261 2/20 0.62
HSD17B10 Q99714 2/20 0.62
PTPRA P18433 1/20 0.62
PTPRB P23467 1/20 0.62
HIF1A Q16665 1/20 0.62
RAPGEF4 Q8WZA2 1/20 0.62
CYP3A4 P08684 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29362358 1.00 MPL (1.00) MPLCTRCNSD2MMP14CASP6
SCHEMBL30371538 1.00 MPL (1.00) MPLCTRCNSD2MMP14CASP6
SCHEMBL7247118 1.00 MPL (1.00) MPLCTRCNSD2MMP14CASP6
SCHEMBL16371185 0.99 MPL (0.97) MPLCTRCNSD2MMP14CASP6
SCHEMBL1774890 0.99 MPL (0.97) MPLCTRCNSD2MMP14CASP6
SCHEMBL24742668 0.89 MPL (0.79) MPLCTRCNSD2MMP14CASP6
SCHEMBL13420016 0.89 MPL (0.79) MPLCTRCMAPTKMT2AGAA
SCHEMBL10049018 0.88 MPL (0.77) MPLCTRCNSD2MMP14CASP6
SCHEMBL27016949 0.87 MPL (0.78) MPLCTRCMMP14MAPTKMT2A
SCHEMBL12459388 0.87 MPL (0.78) MPLCTRCNSD2MMP14CASP6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3916391-B1 A METHOD FOR DETECTING A PROSTATE CANCER BIOMARKER AQSENS HEALTH OY (FI) 2024-02-07 EP claimed
CN-113984720-A Methods for detecting biomarkers of prostate cancer 阿克森斯健康公司 2022-01-28 CN claimed
US-6670387-B1 Thrombocytopenia; hydroxy-1-azo-naphthalene derivatives; 3-hydroxy-4-((2-hydroxy-1-naphthalenyl)azo-)-1-naphthalenesul fonic acid; promoters of thrombopoiesis and megakaryocytopoi esis; enhancing platelet production; agonizing TPO receptor SMITHKLINE BEECHAM CORPORATION 2003-12-30 US claimed
EP-1156804-A4 THROMBOPOIETIN MIMETICS SMITHKLINE BEECHAM CORP (US) 2002-08-07 EP claimed
EP-1156804-A1 THROMBOPOIETIN MIMETICS SMITHKLINE BEECHAM CORPORATION (US) 2001-11-28 EP claimed
WO-2000035446-A1 THROMBOPOIETIN MIMETICS SMITHKLINE BEECHAM CORPORATION (US) 2000-06-22 WO claimed
EP-0061444-B1 METHOD FOR REMOVING HYDROGEN SULFIDE FROM GAS STREAMS UNION OIL COMPANY OF CALIFORNIA (US) 1985-05-22 EP claimed
JP-10337199-A None JP disclosed
US-20240019450-A1 FLUORESCENT SENSORS THE UNIVERSITY OF SYDNEY (AU) 2024-01-18 US disclosed
US-20240019450-A1 FLUORESCENT SENSORS THE UNIVERSITY OF SYDNEY (AU) 2024-01-18 US disclosed
US-20230384498-A1 OPTICALLY ANISOTROPIC FILM, OPTICAL FILM, AND DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-11-30 US disclosed
EP-3752201-B1 SUSPENSION OF NANOSCALE, ORGANIC PARTICLES AND PROCESS FOR PRODUCTION THEREOF UNIV FRIEDRICH ALEXANDER ER (DE) 2023-11-22 EP disclosed
US-20230358935-A1 OPTICAL FILM AND ELECTROLUMINESCENCE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2023-11-09 US disclosed
EP-0473511-A1 Electrically-conductive polymer based material comprising magnetic particles and its production process COMMISSARIAT A L'ENERGIE ATOMIQUE (FR) 1992-03-04 EP disclosed
EP-0356851-A2 Process for the preparation of solutions of 1:2-chromium complex azo dyes BASF Aktiengesellschaft (DE) 1990-03-07 EP disclosed
EP-0198800-B1 PROCESS FOR THE PRODUCTION OF 1-DIAZO-2-NAPHTHOL-4-SULPHONIC ACID CIBA-GEIGY AG (CH) 1988-08-24 EP disclosed
WO-1982001554-A1 POLYCARBONATES STABILIZED BY HALOHYDROCARBON,HALOCARBON OR SILANE GROUPS MCALISTER ROY E 1982-05-13 WO disclosed
US-4303610-A Test kit for field analysis of plant tissue magnesium and calcium PENNZOIL COMPANY (US) 1981-12-01 US disclosed
EP-0036584-A2 Chelating ion exchanger based organic polymer and process for its preparation RIEDEL-DE HAEN AKTIENGESELLSCHAFT (DE) 1981-09-30 EP disclosed
US-4084983-A ALUMINUM FLAKES ON A COATING OF ALUMINUM HYDROXIDE MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) 1978-04-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240019450-A1 FLUORESCENT SENSORS NCS1, TRPA1, AQP1 MPL 4831/4885CTRC 4537/4885NSD2 4516/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.