Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.47 |
| ▸ | IKBKB | O14920 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27189062 | 0.92 | DGAT1 (0.48) | TRPV1IKBKBHTTMEN1KMT2A | |
| SCHEMBL30106359 | 0.91 | GSK3B (0.51) | GSK3BTRPV1IKBKBSMN1; SMN2HDAC3 | |
| SCHEMBL30106324 | 0.90 | NPC1 (0.48) | GSK3BTRPV1IKBKBHTTTRPA1 | |
| SCHEMBL30106351 | 0.89 | TRPV1 (0.49) | GSK3BTRPV1IKBKBMEN1KMT2A | |
| SCHEMBL27189069 | 0.86 | CASP6 (0.50) | GSK3BTRPV1IKBKBHTTMEN1 | |
| SCHEMBL30106349 | 0.86 | CASP6 (0.50) | GSK3BTRPV1IKBKBHTTMEN1 | |
| SCHEMBL27189116 | 0.84 | IKBKB (0.48) | GSK3BTRPV1IKBKBPOLBHDAC3 | |
| SCHEMBL30106393 | 0.83 | CASP6 (0.47) | TRPV1IKBKBHTTMEN1KMT2A | |
| SCHEMBL29158764 | 0.83 | CASP6 (0.47) | TRPV1IKBKBHTTMEN1KMT2A | |
| SCHEMBL30106391 | 0.83 | NPC1 (0.53) | GSK3BTRPV1IKBKBCASP6SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022255764-A1 | NOVEL OXAZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME FOR PREVENTION OR TREATMENT OF ALLERGIC DISEASE | 주식회사 에즈큐리스 | 2022-12-08 | — | — | WO | disclosed |