Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | TSPO | P30536 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30106364 | 0.92 | NPC1 (0.50) | NPC1MAPTSMN1; SMN2S1PR1EGLN1 | |
| SCHEMBL30106348 | 0.90 | GSK3B (0.49) | SMN1; SMN2CASP6MEN1KMT2ATRPA1 | |
| SCHEMBL29158659 | 0.90 | WNT1 (0.49) | NPC1MAPTSMN1; SMN2S1PR1EGLN1 | |
| SCHEMBL30106354 | 0.90 | WNT1 (0.49) | NPC1MAPTSMN1; SMN2S1PR1EGLN1 | |
| SCHEMBL27189062 | 0.89 | DGAT1 (0.48) | SMN1; SMN2CASP6MEN1KMT2AIKBKB | |
| SCHEMBL27189069 | 0.85 | CASP6 (0.50) | NPC1MAPTCASP6MEN1KMT2A | |
| SCHEMBL30106349 | 0.85 | CASP6 (0.50) | NPC1MAPTCASP6MEN1KMT2A | |
| SCHEMBL30106371 | 0.84 | WNT1 (0.45) | NPC1EGLN1PDE10ATSPO | |
| SCHEMBL30740873 | 0.82 | TARBP2 (0.52) | NPC1MAPTSMN1; SMN2S1PR1MEN1 | |
| SCHEMBL30106351 | 0.82 | TRPV1 (0.49) | NPC1MAPTSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022255764-A1 | NOVEL OXAZOLE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME FOR PREVENTION OR TREATMENT OF ALLERGIC DISEASE | 주식회사 에즈큐리스 | 2022-12-08 | — | — | WO | disclosed |