Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26668132 | 0.78 | KCNN4 (0.34) | ADRB3CYP26A1KCNN4ELANEAR | |
| SCHEMBL10473438 | 0.78 | ELANE (0.33) | ADRB3KCNN4KCNA3ELANE | |
| SCHEMBL3095800 | 0.78 | LMNA (0.47) | ADRB3KCNN4KCNA3ELANE | |
| SCHEMBL11264498 | 0.76 | — | — | |
| SCHEMBL11264511 | 0.76 | — | — | |
| SCHEMBL26668633 | 0.76 | NOS1 (0.38) | ADRB3KCNN4KCNA3ELANE | |
| SCHEMBL16886284 | 0.76 | KCNN4 (0.34) | ADRB3KCNN4KCNA3ELANE | |
| SCHEMBL16422823 | 0.74 | ELANE (0.32) | ADRB3KCNN4KCNA3ELANE | |
| SCHEMBL30107133 | 0.73 | KMT2A (0.36) | ADRB3ELANE | |
| SCHEMBL16861392 | 0.72 | NOS1 (0.34) | ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110678466-B | Diazanaphthalenes as HPK1 inhibitors | 豪夫迈·罗氏有限公司 | 2023-01-31 | — | — | CN | disclosed |