Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 16/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 15/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 12/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 12/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30107981 | 0.82 | ADORA2A (0.42) | ADORA2AADORA1ADORA3ADORA2BPIK3R1 | |
| SCHEMBL30107999 | 0.81 | ADORA2A (0.44) | ADORA2AADORA1ADORA3ADORA2BPIK3R1 | |
| SCHEMBL30108046 | 0.78 | KDM4E (0.39) | ADORA2AADORA1ADORA3ADORA2BCCNA2 | |
| SCHEMBL30108010 | 0.74 | ALDH1A1 (0.41) | ADORA2AADORA1ADORA3ADORA2BMAPK14 | |
| SCHEMBL30107947 | 0.71 | ALDH1A1 (0.42) | ADORA2AADORA1ADORA3ADORA2BMAPK14 | |
| SCHEMBL30108071 | 0.71 | KDM4E (0.39) | ADORA2AADORA1ADORA3ADORA2BCCNA2 | |
| SCHEMBL30108068 | 0.69 | AXL (0.35) | ADORA2AADORA1ADORA3ADORA2B | |
| SCHEMBL3455589 | 0.68 | ADORA2A (0.55) | ADORA2AADORA1ADORA3ADORA2BPIK3R1 | |
| SCHEMBL5453909 | 0.65 | DHFR (0.51) | ADORA2AADORA1ADORA3ADORA2BPIK3R1 | |
| SCHEMBL3455110 | 0.64 | ADORA2A (0.58) | ADORA2AADORA1ADORA2BPIK3R1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022203399-A1 | ADENOSINE A2A RECEPTOR ANTAGONIST AND USE THEREOF | 주식회사 스탠다임 | 2022-09-29 | — | — | WO | disclosed |