Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.36 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30107947 | 0.81 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDMAPTRAB9A | |
| SCHEMBL30108020 | 0.74 | ADORA2A (0.39) | PIK3R1PIK3CAADORA3ADORA2AADORA2B | |
| SCHEMBL30107981 | 0.73 | ADORA2A (0.42) | PIK3R1PIK3CAADORA3ADORA2AADORA2B | |
| SCHEMBL30107999 | 0.71 | ADORA2A (0.44) | ALDH1A1KDM4EHPGDMAPTPTPN7 | |
| SCHEMBL30107990 | 0.70 | ALDH1A1 (0.37) | ALDH1A1KDM4EHPGDMAPTRAB9A | |
| SCHEMBL30108053 | 0.68 | PDGFRB (0.37) | ALDH1A1KDM4EMAPTHTTPOLB | |
| SCHEMBL30107951 | 0.65 | PTGS1 (0.46) | ALDH1A1KDM4EHPGDMAPTRAB9A | |
| SCHEMBL30107973 | 0.65 | KDM4E (0.46) | ALDH1A1KDM4EHPGDMAPTRAB9A | |
| SCHEMBL19848195 | 0.65 | ALDH1A1 (0.45) | ALDH1A1KDM4EMAPTRAB9ATDP1 | |
| SCHEMBL30108013 | 0.63 | HPGD (0.53) | ALDH1A1KDM4EHPGDMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022203399-A1 | ADENOSINE A2A RECEPTOR ANTAGONIST AND USE THEREOF | 주식회사 스탠다임 | 2022-09-29 | — | — | WO | disclosed |