Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PTPRA | P18433 | 1/20 | 0.33 |
| ▸ | PTPRB | P23467 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30926166 | 0.81 | RAB9A (0.46) | RAB9ANPC1ALDH1A1HPGDHTT | |
| SCHEMBL21000677 | 0.73 | RAB9A (0.43) | RAB9ANPC1ALDH1A1HPGDGAA | |
| SCHEMBL30429916 | 0.69 | RAB9A (0.58) | RAB9ANPC1ALDH1A1HPGDGAA | |
| SCHEMBL2245316 | 0.69 | RAB9A (0.58) | RAB9ANPC1ALDH1A1HPGDGAA | |
| SCHEMBL19452558 | 0.68 | NPC1 (0.42) | RAB9ANPC1ALDH1A1HPGDGAA | |
| SCHEMBL388593 | 0.67 | HSD17B10 (0.53) | PTPN11ALDH1A1GAAHSD17B10CYP2C9 | |
| SCHEMBL2964080 | 0.66 | MIF (0.60) | RAB9ANPC1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL10770352 | 0.66 | HDAC6 (0.66) | RAB9ANPC1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL10770346 | 0.66 | RAB9A (0.61) | PTPN11PTGS2RAB9ANPC1ALDH1A1 | |
| SCHEMBL14514049 | 0.65 | ALDH1A1 (0.62) | PTPN11ALDH1A1HPGDGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115417833-B | Synthesis method of 2-amido naphtho [1,2-d ] thiazole | 池州学院 | 2024-05-28 | — | — | CN | disclosed |
| CN-115417833-A | Synthesis method of 2-acylamino naphtho [1,2-d ] thiazole | 池州学院 | 2022-12-02 | — | — | CN | disclosed |