Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30108295 | 0.78 | CYP2C9 (0.35) | POLBALDH1A1USP2CYP1A2CYP2C9 | |
| SCHEMBL30108294 | 0.78 | CYP2D6 (0.38) | POLBALDH1A1USP2CYP1A2CYP2C9 | |
| SCHEMBL18095946 | 0.77 | EPHX1 (0.37) | POLBALDH1A1USP2CYP1A2CYP2C9 | |
| SCHEMBL2081988 | 0.74 | KMT2A (0.54) | POLBALDH1A1USP2CYP1A2CYP2C9 | |
| SCHEMBL711832 | 0.71 | ATM (0.34) | CYP1A2CYP2C9CYP2C19LMNATSHR | |
| SCHEMBL20303735 | 0.70 | OPRK1 (0.32) | LMNA | |
| SCHEMBL9610 | 0.70 | ATM (0.33) | POLBALDH1A1CYP1A2CYP2C9CYP2D6 | |
| SCHEMBL15046910 | 0.68 | — | — | |
| SCHEMBL853368 | 0.68 | CHRNB2 (0.35) | CHRNB2CHRNA4CHRNB4CHRNA3 | |
| SCHEMBL3622678 | 0.68 | EPHX1 (0.40) | ALDH1A1USP2CYP1A2CYP2C9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113549068-B | Novel imidazopyridine compound, preparation method and medical application thereof | 上海拓界生物医药科技有限公司 | 2022-12-02 | — | — | CN | disclosed |