Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA3 | P22001 | 1/20 | 0.62 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.59 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.59 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.59 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.59 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.55 |
| ▸ | APP | P05067 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30108320 | 0.98 | KCNA3 (0.65) | KCNA3CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL28942158 | 0.91 | LTA4H (0.66) | KCNA3CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL28942149 | 0.88 | LTA4H (0.66) | KCNA3CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL14232324 | 0.82 | CHRNB2 (0.58) | KCNA3CHRNB2CHRNB4CHRNA3CHRNA7 | |
| SCHEMBL9011596 | 0.81 | KCNA3 (0.94) | KCNA3HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL2512157 | 0.81 | KCNA3 (0.94) | KCNA3HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL31229544 | 0.81 | KCNA3 (0.94) | KCNA3HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL497029 | 0.81 | KCNA3 (0.94) | KCNA3HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL10904079 | 0.81 | KCNA3 (0.94) | KCNA3HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL28576557 | 0.81 | KCNA3 (0.94) | KCNA3HDAC1HDAC2HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115651193-B | Polysubstituted polyquinoline and preparation method and application thereof | 深圳大学 | 2023-12-01 | — | — | CN | disclosed |
| CN-116462843-A | Polysubstituted nitrogen-sulfur-containing fused heterocyclic polymer and preparation method and application thereof | 深圳大学 | 2023-07-21 | — | — | CN | disclosed |
| CN-115651193-A | Polysubstituted polyquinoline and preparation method and application thereof | 深圳大学 | 2023-01-31 | — | — | CN | disclosed |