SCHEMBL30110196

SCHEMBL30110196

CC(=O)c1cc2cc(Br)cc(Br)c2oc1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOB P27338 11/20 1.00
GPR35 Q9HC97 3/20 0.74
MAOA P21397 7/20 0.73
ALDH1A1 P00352 3/20 0.62
HPGD P15428 1/20 0.62
MAPT P10636 3/20 0.57
THRB P10828 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17037289 1.00 MAOB (1.00) MAOBGPR35MAOAALDH1A1HPGD
SCHEMBL1367003 0.87 GPR35 (0.79) MAOBGPR35MAOAALDH1A1HPGD
SCHEMBL3080344 0.85 GPR35 (1.00) MAOBGPR35MAOAALDH1A1HPGD
SCHEMBL30110368 0.84 GPR35 (0.74) MAOBGPR35MAOAALDH1A1HPGD
SCHEMBL3087456 0.81 MAOB (0.68) MAOBGPR35MAOAALDH1A1HPGD
SCHEMBL3091303 0.80 MAOB (0.77) MAOBGPR35MAOAALDH1A1HPGD
SCHEMBL16795821 0.78 MAOB (0.64) MAOBGPR35MAOAALDH1A1HPGD
SCHEMBL980429 0.74 MAOA (1.00) MAOBGPR35MAOAALDH1A1HPGD
SCHEMBL17037290 0.71 GPR35 (0.74) MAOBGPR35MAOAALDH1A1HPGD
SCHEMBL22041605 0.71 GPR35 (0.74) MAOBGPR35MAOAALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115368333-B Ibuprofen-coumarin skeleton-containing compound and application thereof 湖北医药学院 2024-11-19 CN disclosed
CN-115368333-A Compound containing ibuprofen-coumarin skeleton and application thereof 湖北医药学院 2022-11-22 CN disclosed