Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 6/20 | 0.41 |
| ▸ | HTR3A | P46098 | 3/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29892144 | 0.86 | CHRNA7 (0.52) | LCKCHRNA7HTR3AHTR3EHTR3B | |
| SCHEMBL6263910 | 0.86 | CHRNA7 (0.52) | LCKCHRNA7HTR3AHTR3EHTR3B | |
| SCHEMBL844863 | 0.84 | KMO (0.54) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL844237 | 0.79 | LCK (0.48) | LCKCHRNA7HTR3AALDH1A1NTRK1 | |
| SCHEMBL6844308 | 0.75 | CHRNA7 (0.40) | CHRNA7HTR3AHTR3EHTR3BHTR3D | |
| SCHEMBL5173369 | 0.75 | LCK (0.56) | LCKSIRT6KMT2AAPPLMNA | |
| SCHEMBL10859259 | 0.72 | CYP2A6 (0.36) | KMOALDH1A1DYRK1A | |
| SCHEMBL23088144 | 0.71 | DYRK1A (0.37) | DYRK1A | |
| SCHEMBL10555583 | 0.71 | ALDH1A1 (0.36) | KMOALDH1A1DYRK1A | |
| SCHEMBL678365 | 0.71 | LCK (0.53) | LCKCHRNA7ALDH1A1SIRT6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115667259-B | Fused ring compounds for inhibiting H-PGDS | 佐藤制药株式会社 | 2025-06-17 | — | — | CN | disclosed |
| CN-115667259-A | Condensed ring compounds for inhibiting H-PGDS | 佐藤制药株式会社 | 2023-01-31 | — | — | CN | disclosed |