Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.43 |
| ▸ | LTB4R | Q15722 | 7/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 7/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8497028 | 0.81 | IGLV6-57 (0.51) | IGLV6-57FFAR1ALOX5KCNH2SCN3A | |
| SCHEMBL15193542 | 0.80 | ALDH1A1 (0.46) | TDP1MEN1KMT2ABRD4 | |
| SCHEMBL29636289 | 0.80 | ALDH1A1 (0.46) | TDP1MEN1KMT2ABRD4 | |
| SCHEMBL10269886 | 0.77 | CA1 (0.53) | FFAR1ALOX5KCNH2SCN3ALTB4R | |
| SCHEMBL6904351 | 0.75 | FFAR1 (0.61) | IGLV6-57FFAR1ALOX5KCNH2SCN3A | |
| SCHEMBL25408444 | 0.75 | LMNA (0.43) | TDP1MEN1KMT2A | |
| SCHEMBL15156136 | 0.75 | CA1 (0.55) | TDP1 | |
| SCHEMBL13577180 | 0.74 | IGLV6-57 (0.51) | IGLV6-57FFAR1ALOX5KCNH2SCN3A | |
| SCHEMBL5715746 | 0.73 | FFAR1 (0.51) | IGLV6-57FFAR1ALOX5LTB4RLTB4R2 | |
| SCHEMBL257849 | 0.72 | FFAR1 (0.54) | IGLV6-57FFAR1ALOX5KCNH2SCN3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115124534-A | Non-nucleotide PRMT5 small molecule inhibitor, preparation method and application | 中山大学 | 2022-09-30 | — | — | CN | disclosed |