Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 5/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 5/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.34 |
| ▸ | P4HB | P07237 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30110762 | 0.86 | LPL (0.44) | LPLLIPGRORCPRMT5SLC6A4 | |
| SCHEMBL1328329 | 0.84 | LPL (0.45) | LPLLIPGROCK1EGFRAAK1 | |
| SCHEMBL253525 | 0.81 | LPL (0.45) | LPLLIPGROCK1EGFRAAK1 | |
| SCHEMBL29556201 | 0.81 | LPL (0.45) | LPLLIPGROCK1EGFRAAK1 | |
| SCHEMBL4366318 | 0.79 | LPL (0.47) | LPLLIPGROCK1SLC6A4P4HB | |
| SCHEMBL30111074 | 0.78 | LPL (0.54) | LPLLIPGP4HBDGAT1ESR2 | |
| SCHEMBL30110731 | 0.78 | LPL (0.54) | LPLLIPGP4HBDGAT1ESR2 | |
| SCHEMBL18582905 | 0.77 | LPL (0.39) | LPLLIPGRORCSLC6A4P4HB | |
| SCHEMBL18582906 | 0.77 | LPL (0.39) | LPLLIPGRORCSLC6A4P4HB | |
| SCHEMBL142144 | 0.76 | LPL (0.49) | LPLLIPGROCK1EGFRCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115124534-B | Non-nucleotide PRMT5 small molecule inhibitor, preparation method and application | 中山大学 | 2023-09-15 | — | — | CN | disclosed |
| CN-115124534-A | Non-nucleotide PRMT5 small molecule inhibitor, preparation method and application | 中山大学 | 2022-09-30 | — | — | CN | disclosed |