Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 6/20 | 0.44 |
| ▸ | LIPG | Q9Y5X9 | 6/20 | 0.44 |
| ▸ | RORC | P51449 | 2/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | P4HB | P07237 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 2/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30110754 | 0.86 | LPL (0.43) | LPLLIPGRORCAAK1SLC6A4 | |
| SCHEMBL14552656 | 0.83 | LPL (0.40) | LPLLIPGAAK1CSF1RESR2 | |
| SCHEMBL2412157 | 0.79 | LPL (0.41) | LPLLIPGAAK1CSF1RESR2 | |
| SCHEMBL30111074 | 0.79 | LPL (0.54) | LPLLIPGIGLV6-57P4HBESR2 | |
| SCHEMBL30110731 | 0.79 | LPL (0.54) | LPLLIPGIGLV6-57P4HBESR2 | |
| SCHEMBL18582905 | 0.78 | LPL (0.39) | LPLLIPGRORCAAK1SLC6A4 | |
| SCHEMBL18582906 | 0.78 | LPL (0.39) | LPLLIPGRORCAAK1SLC6A4 | |
| SCHEMBL1129289 | 0.78 | LIPG (0.49) | LPLLIPGP4HBCSF1RDGAT1 | |
| SCHEMBL22290696 | 0.76 | LIPG (0.43) | LPLLIPGIGLV6-57P4HBDGAT1 | |
| SCHEMBL796915 | 0.75 | CSF1R (0.49) | LPLLIPGAAK1CSF1RCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115124534-B | Non-nucleotide PRMT5 small molecule inhibitor, preparation method and application | 中山大学 | 2023-09-15 | — | — | CN | disclosed |
| CN-115124534-A | Non-nucleotide PRMT5 small molecule inhibitor, preparation method and application | 中山大学 | 2022-09-30 | — | — | CN | disclosed |