Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 16/20 | 0.51 |
| ▸ | PGR | P06401 | 4/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | RXRG | P48443 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30112105 | 0.83 | MAPT (0.47) | PGRMAPTEGLN2 | |
| SCHEMBL28972462 | 0.81 | RXRA (0.49) | ARPGRRXRARXRBRXRG | |
| SCHEMBL30112131 | 0.81 | AR (0.55) | ARPGRRXRARXRBRXRG | |
| SCHEMBL12128119 | 0.80 | MAPT (0.47) | PGRMAPT | |
| SCHEMBL30112143 | 0.80 | MAPT (0.47) | ARPGRMAPTEGLN2 | |
| SCHEMBL28972461 | 0.80 | AR (0.45) | ARPGRRXRARXRBRXRG | |
| SCHEMBL30112118 | 0.79 | CYP3A4 (0.42) | ARPGRMAPT | |
| SCHEMBL29213634 | 0.78 | PRF1 (0.59) | PGRMAPT | |
| SCHEMBL13004388 | 0.77 | HSD17B1 (0.51) | PGRMAPT | |
| SCHEMBL12127710 | 0.76 | MAPT (0.39) | PGRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110016011-B | Amide derivative and medical use thereof | 北京美倍他药物研究有限公司 | 2023-02-03 | — | — | CN | disclosed |