Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 3/20 | 0.47 |
| ▸ | CCR8 | P51685 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | CCR5 | P51681 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30112679 | 0.94 | KDM4E (0.53) | CCR1CCR8KDM4ECCR5LMNA | |
| SCHEMBL17899337 | 0.87 | CCR1 (0.61) | CCR1CCR8KDM4ECCR5LMNA | |
| SCHEMBL16852209 | 0.86 | CCR1 (0.52) | CCR1CCR8KDM4ECCR5LMNA | |
| SCHEMBL11962211 | 0.86 | CCR1 (0.64) | CCR1CCR8KDM4ECCR5LMNA | |
| SCHEMBL19486732 | 0.86 | MAPT (0.44) | CCR1CCR8KDM4ECCR5LMNA | |
| SCHEMBL19486694 | 0.85 | TOP1 (0.48) | CCR1CCR8KDM4ECCR5LMNA | |
| SCHEMBL17174057 | 0.84 | KDM4E (0.57) | CCR1CCR8KDM4ECCR5LMNA | |
| SCHEMBL30449837 | 0.84 | LMNA (0.61) | CCR1CCR8KDM4ECCR5LMNA | |
| SCHEMBL1395123 | 0.84 | LMNA (0.61) | CCR1CCR8KDM4ECCR5LMNA | |
| SCHEMBL21841075 | 0.84 | TOP1 (0.53) | CCR1CCR8KDM4ECCR5LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110028504-B | Preparation method and application of 2, 9-diaryl substituted o-phenanthroline and cobalt complex thereof | 南开大学（CN） | 2023-01-13 | — | — | CN | claimed |
| CN-112805005-B | Thyroxine receptor beta agonist compounds | 拓臻股份有限公司 | 2026-05-12 | — | — | CN | disclosed |
| CN-119552115-A | Heterocyclic compound and application thereof in medicine | 康百达（四川）生物医药科技有限公司 | 2025-03-04 | — | — | CN | disclosed |
| CN-119285613-A | Substituted quinoxaline and quinazolinone compounds and uses thereof | 河南中医药大学 | 2025-01-10 | — | — | CN | disclosed |
| CN-113454097-B | Tubulysin and protein-tubulysin conjugates | 里珍纳龙药品有限公司 | 2024-08-30 | — | — | CN | disclosed |
| CN-115843271-B | Indole derivatives and their use for the treatment of cancer | 克洛德贝纳尔-里昂第一大学 | 2024-08-13 | — | — | CN | disclosed |
| CN-118055927-A | Substituted phenylpropionic acid derivative and application thereof | 上海拓界生物医药科技有限公司 | 2024-05-17 | — | — | CN | disclosed |
| CN-117185987-A | Amidine and guanidine derivatives, preparation method and medical application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-117083274-A | Fused ring heterocyclic derivative and application thereof in medicine | 四川海思科制药有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-111630048-B | Amidine and guanidine derivatives, preparation method and medical application thereof | 四川科伦博泰生物医药股份有限公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-116514817-A | Heterocyclic compound with AKT kinase inhibition activity, preparation method and medical application thereof | 中国医药研究开发中心有限公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-112010858-B | BTK inhibitor, preparation method and pharmaceutical application thereof | 四川海思科制药有限公司 | 2023-07-18 | — | — | CN | disclosed |
| CN-114717211-B | Imine reductase mutant M5 and application thereof in synthesis of nitrogen heterocycle chiral amine | 江苏集萃分子工程研究院有限公司 | 2023-06-02 | — | — | CN | disclosed |
| CN-115843271-A | Indole derivatives and their use for the treatment of cancer | 克洛德贝纳尔-里昂第一大学 | 2023-03-24 | — | — | CN | disclosed |
| CN-113121574-B | Purine derivatives and their use in medicine | 成都百裕制药股份有限公司 | 2023-02-17 | — | — | CN | disclosed |
| CN-110028504-B | Preparation method and application of 2, 9-diaryl substituted o-phenanthroline and cobalt complex thereof | 南开大学（CN） | 2023-01-13 | — | — | CN | disclosed |