Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28372455 | 1.00 | KDM4E (0.40) | KDM4EHPGDMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL30112834 | 0.91 | ABCG2 (0.38) | KDM4EHPGDMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL28367488 | 0.80 | ABCG2 (0.50) | KDM4EHPGDMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL15876264 | 0.80 | HPGD (0.44) | KDM4EHPGDMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL25824780 | 0.76 | ANO1 (0.43) | KDM4EHPGDMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL25824896 | 0.73 | LPL (0.55) | KDM4EHPGDMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL9080216 | 0.72 | CYP3A4 (0.72) | KDM4EHPGDMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL12160830 | 0.71 | L3MBTL1 (0.41) | HPGDALDH1A1SMN1; SMN2ABCG2CYP3A4 | |
| SCHEMBL29997597 | 0.71 | ANO1 (0.39) | KDM4EMAPTALDH1A1SMN1; SMN2ABCG2 | |
| SCHEMBL28327248 | 0.71 | ANO1 (0.39) | KDM4EMAPTALDH1A1SMN1; SMN2ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110746393-B | Synthesis method of 3-methylthio substituted benzofuran compound | 河北凯诺中星科技有限公司 | 2023-01-06 | — | — | CN | disclosed |