Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 3/20 | 0.50 |
| ▸ | LIPE | Q05469 | 1/20 | 0.49 |
| ▸ | CCR6 | P51684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 2/20 | 0.45 |
| ▸ | MMP9 | P14780 | 2/20 | 0.45 |
| ▸ | MMP13 | P45452 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30114488 | 0.87 | BMP1 (0.60) | BMP1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL22718099 | 0.85 | BMP1 (0.46) | BMP1CCR6MAPTKDM4EMEN1 | |
| SCHEMBL24497371 | 0.83 | BMP1 (0.44) | BMP1LIPECCR6MAPTKDM4E | |
| SCHEMBL29648392 | 0.83 | BMP1 (0.44) | BMP1LIPECCR6MAPTKDM4E | |
| SCHEMBL29648375 | 0.83 | MAPT (0.44) | BMP1LIPECCR6MAPTKDM4E | |
| SCHEMBL24497405 | 0.83 | MAPT (0.44) | BMP1LIPECCR6MAPTKDM4E | |
| SCHEMBL29648360 | 0.81 | MAPT (0.42) | BMP1LIPECCR6MAPTKDM4E | |
| SCHEMBL24497376 | 0.81 | MAPT (0.42) | BMP1LIPECCR6MAPTKDM4E | |
| SCHEMBL24879920 | 0.80 | CCR6 (0.40) | BMP1LIPECCR6MAPTKDM4E | |
| SCHEMBL22718255 | 0.80 | MMP1 (0.40) | BMP1LIPECCR6MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594680-A | TEAD inhibitor | 武汉人福创新药物研发中心有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |
| WO-2023280254-A1 | TEAD INHIBITOR | 武汉人福创新药物研发中心有限公司 | 2023-01-12 | — | — | WO | disclosed |