Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 3/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.49 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30114634 | 0.87 | BMP1 (0.50) | BMP1ALDH1A1NR1H3PTGER1KDM4E | |
| SCHEMBL24880306 | 0.86 | BMP1 (0.52) | BMP1ALDH1A1NR1H3PTGER1KDM4E | |
| SCHEMBL24497433 | 0.82 | BMP1 (0.47) | BMP1ALDH1A1NR1H3PTGER1KDM4E | |
| SCHEMBL24497406 | 0.80 | BMP1 (0.43) | BMP1PTGER1KDM4EKMT2ALMNA | |
| SCHEMBL30114163 | 0.79 | ALDH1A1 (0.46) | BMP1ALDH1A1LMNATAS2R14MMP9 | |
| SCHEMBL6958238 | 0.78 | TAS2R14 (0.64) | ALDH1A1KMT2ATAS2R14 | |
| SCHEMBL10994568 | 0.77 | GAA (0.68) | ALDH1A1KDM4EKMT2ATP53MAPT | |
| SCHEMBL30114282 | 0.76 | ALDH1A1 (0.43) | BMP1ALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL29966020 | 0.76 | LMNA (0.63) | ALDH1A1KMT2ATP53LMNAMAPT | |
| SCHEMBL30014545 | 0.75 | APLNR (0.51) | KMT2ALMNATAS2R14MEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594680-A | TEAD inhibitor | 武汉人福创新药物研发中心有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |