Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 5/20 | 0.38 |
| ▸ | ACE | P12821 | 2/20 | 0.38 |
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
| ▸ | APLNR | P35414 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29384990 | 0.92 | ACE (0.38) | MMEACEECE1 | |
| SCHEMBL29894779 | 0.89 | MME (0.46) | MMEACE | |
| SCHEMBL30974254 | 0.89 | OPRM1 (0.39) | MMEECE1 | |
| SCHEMBL30547095 | 0.87 | ACE (0.43) | MMEACEECE1KDM4EMAPT | |
| SCHEMBL21828612 | 0.87 | ACE (0.36) | MMEACE | |
| SCHEMBL29374335 | 0.87 | ACE (0.36) | MMEACE | |
| SCHEMBL31433276 | 0.87 | ACE (0.39) | MMEACE | |
| SCHEMBL29461560 | 0.86 | MME (0.39) | MMEACE | |
| SCHEMBL29532207 | 0.85 | MME (0.41) | MME | |
| SCHEMBL29849128 | 0.85 | MME (0.36) | MMEACEECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3526233-B1 | PEPTIDES DERIVED FROM FIBRONECTIN WITH IMPROVED BIOACTIVITY AND REDUCED SUSCEPTIBILITY TO NEUTROPHIL ELASTASE DEGRADATION | NEOMATRIX THERAPEUTICS INC (US) | 2025-01-15 | — | — | EP | disclosed |
| US-20230331814-A1 | PEPTIDES DERIVED FROM FIBRONECTIN WITH IMPROVED BIOACTIVITY AND REDUCED SUSCEPTIBILITY TO NEUTROPHIL ELASTASE DEGRADATION | NEOMATRIX THERAPEUTICS INC (US) | 2023-10-19 | — | — | US | disclosed |
| US-11548935-B2 | Peptides derived from fibronectin with improved bioactivity and reduced susceptibility to neutrophil elastase degradation | Neomatrix Therapeutics Inc. (US) | 2023-01-10 | — | — | US | disclosed |