Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 14/20 | 0.39 |
| ▸ | MME | P08473 | 12/20 | 0.38 |
| ▸ | CPA1 | P15085 | 10/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 10/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15011307 | 0.91 | ACE (0.42) | ACEMMECPA1ACE2 | |
| SCHEMBL30874984 | 0.91 | ACE (0.42) | ACEMMECPA1ACE2 | |
| SCHEMBL15011306 | 0.91 | ACE (0.42) | ACEMMECPA1ACE2 | |
| SCHEMBL20397486 | 0.89 | ANPEP (0.40) | — | |
| SCHEMBL29615610 | 0.88 | CTSD (0.37) | MME | |
| SCHEMBL30547095 | 0.88 | ACE (0.43) | ACEMME | |
| SCHEMBL31020879 | 0.87 | ACE (0.38) | ACE | |
| SCHEMBL30918507 | 0.87 | MAGI3 (0.37) | ACEMMECPA1ACE2 | |
| SCHEMBL30116291 | 0.87 | MME (0.38) | ACEMME | |
| SCHEMBL31318666 | 0.86 | ENPEP (0.41) | ACEMMECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250074942-A1 | COMPOSITIONS AND METHODS FOR COVALENT PEPTIDE-BASED MODULATORS OF HLA-E | CALICO LIFE SCIENCES LLC (US) | 2025-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250074942-A1 | COMPOSITIONS AND METHODS FOR COVALENT PEPTIDE-BASED MODULATORS OF HLA-E | MICA, CD74, HLA-DRB1 | ACE 2383/4885MME 130/4885CPA1 1822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.