SCHEMBL30116357

NCCCC[C@H](NC(=O)[C@@H](N)CO)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	OPRD1	P41143	8/20	0.56

▸	OPRM1	P35372	6/20	0.56

▸	ACE	P12821	2/20	0.47

▸	NPFFR1	Q9GZQ6	1/20	0.46

▸	NPFFR2	Q9Y5X5	1/20	0.46

▸	NTSR2	O95665	1/20	0.46

▸	NTSR1	P30989	1/20	0.46

▸	SORT1	Q99523	1/20	0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30439746	1.00	OPRD1 (0.56)	OPRD1OPRM1ACENPFFR1NPFFR2
SCHEMBL29392400	1.00	OPRD1 (0.56)	OPRD1OPRM1ACENPFFR1NPFFR2
SCHEMBL30503059	1.00	OPRD1 (0.56)	OPRD1OPRM1ACENPFFR1NPFFR2
SCHEMBL29531591	0.99	OPRD1 (0.57)	OPRD1OPRM1ACE
SCHEMBL30439569	0.99	OPRD1 (0.57)	OPRD1OPRM1ACE
SCHEMBL30116348	0.99	OPRD1 (0.57)	OPRD1OPRM1ACE
SCHEMBL30439763	0.98	OPRD1 (0.56)	OPRD1OPRM1ACE
SCHEMBL30533414	0.97	OPRD1 (0.59)	OPRD1OPRM1ACENPFFR1NPFFR2
SCHEMBL30116346	0.96	OPRD1 (0.59)	OPRD1OPRM1ACENPFFR1NPFFR2
SCHEMBL30116343	0.96	OPRD1 (0.59)	OPRD1OPRM1ACENPFFR1NPFFR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-115697375-A	Pharmaceutical composition comprising GLP-2 derivatives or long-acting conjugates thereof for the prevention or treatment of mucositis induced by radiotherapy, chemotherapy or a combination thereof	韩美药品株式会社	2023-02-03	—	—	CN	disclosed