Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 9/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.57 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30116348 | 1.00 | OPRD1 (0.57) | OPRD1OPRM1ACEBDKRB2 | |
| SCHEMBL29531591 | 0.99 | OPRD1 (0.57) | OPRD1OPRM1ACEBDKRB2 | |
| SCHEMBL30503059 | 0.99 | OPRD1 (0.56) | OPRD1OPRM1ACE | |
| SCHEMBL30439746 | 0.99 | OPRD1 (0.56) | OPRD1OPRM1ACE | |
| SCHEMBL29392400 | 0.99 | OPRD1 (0.56) | OPRD1OPRM1ACE | |
| SCHEMBL30116357 | 0.99 | OPRD1 (0.56) | OPRD1OPRM1ACE | |
| SCHEMBL30439763 | 0.98 | OPRD1 (0.56) | OPRD1OPRM1ACEBDKRB2 | |
| SCHEMBL30116343 | 0.97 | OPRD1 (0.59) | OPRD1OPRM1ACE | |
| SCHEMBL30631183 | 0.96 | OPRD1 (0.60) | OPRD1OPRM1BDKRB2 | |
| SCHEMBL31121205 | 0.96 | OPRD1 (0.55) | OPRD1OPRM1BDKRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116635050-A | Novel triple agonists active on all of glucagon, GLP-1 and GIP receptors and uses thereof | 韩美药品株式会社 | 2023-08-22 | — | — | CN | disclosed |
| CN-116635055-A | Pharmaceutical composition for preventing or treating lupus-related diseases comprising GIP derivative or long-acting conjugate thereof | 韩美药品株式会社 | 2023-08-22 | — | — | CN | disclosed |
| CN-116600831-A | Triple agonists or conjugates thereof active on all of glucagon, GLP-1 and GLP receptors for the treatment of neurodegenerative diseases | 韩美药品株式会社 | 2023-08-15 | — | — | CN | disclosed |
| CN-116583533-A | GIP derivative, long-acting conjugate thereof and pharmaceutical composition comprising the same | 韩美药品株式会社 | 2023-08-11 | — | — | CN | disclosed |
| CN-116437967-A | Pharmaceutical composition for preventing or treating bone diseases comprising triple agonists or conjugates thereof having activity on all of glucagon, GLP-1 and GLP receptors | 韩美药品株式会社 | 2023-07-14 | — | — | CN | disclosed |
| CN-116419766-A | Therapeutic use of long-acting conjugates of triple agonists acting on all of the glucagon, GLP-1 and GIP receptors against multiple sclerosis | 韩美药品株式会社 | 2023-07-11 | — | — | CN | disclosed |
| CN-116419765-A | GLP-1/GIP dual agonists, long acting conjugates thereof and pharmaceutical compositions comprising the same | 韩美药品株式会社 | 2023-07-11 | — | — | CN | disclosed |
| CN-116390769-A | Pharmaceutical composition for preventing or treating lupus-related diseases comprising glucagon/GLP-1/GIP triple agonist or long-acting conjugate thereof | 韩美药品株式会社 | 2023-07-04 | — | — | CN | disclosed |
| CN-116322645-A | Liquid formulations of long acting conjugates of GLP-2 | 韩美药品株式会社 | 2023-06-23 | — | — | CN | disclosed |
| CN-116209475-A | Therapeutic uses comprising a triple agonist long-acting conjugate or a combination of triple agonists | 韩美药品株式会社 | 2023-06-02 | — | — | CN | disclosed |