Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 8/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.56 |
| ▸ | ACE | P12821 | 2/20 | 0.47 |
| ▸ | NPFFR1 | Q9GZQ6 | 1/20 | 0.46 |
| ▸ | NPFFR2 | Q9Y5X5 | 1/20 | 0.46 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.46 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.46 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30116357 | 1.00 | OPRD1 (0.56) | OPRD1OPRM1ACENPFFR1NPFFR2 | |
| SCHEMBL29392400 | 1.00 | OPRD1 (0.56) | OPRD1OPRM1ACENPFFR1NPFFR2 | |
| SCHEMBL30503059 | 1.00 | OPRD1 (0.56) | OPRD1OPRM1ACENPFFR1NPFFR2 | |
| SCHEMBL29531591 | 0.99 | OPRD1 (0.57) | OPRD1OPRM1ACE | |
| SCHEMBL30439569 | 0.99 | OPRD1 (0.57) | OPRD1OPRM1ACE | |
| SCHEMBL30116348 | 0.99 | OPRD1 (0.57) | OPRD1OPRM1ACE | |
| SCHEMBL30439763 | 0.98 | OPRD1 (0.56) | OPRD1OPRM1ACE | |
| SCHEMBL30533414 | 0.97 | OPRD1 (0.59) | OPRD1OPRM1ACENPFFR1NPFFR2 | |
| SCHEMBL30116346 | 0.96 | OPRD1 (0.59) | OPRD1OPRM1ACENPFFR1NPFFR2 | |
| SCHEMBL30116343 | 0.96 | OPRD1 (0.59) | OPRD1OPRM1ACENPFFR1NPFFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116419765-A | GLP-1/GIP dual agonists, long acting conjugates thereof and pharmaceutical compositions comprising the same | 韩美药品株式会社 | 2023-07-11 | — | — | CN | disclosed |
| CN-116390769-A | Pharmaceutical composition for preventing or treating lupus-related diseases comprising glucagon/GLP-1/GIP triple agonist or long-acting conjugate thereof | 韩美药品株式会社 | 2023-07-04 | — | — | CN | disclosed |