Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C5AR1 | P21730 | 2/20 | 0.57 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.56 |
| ▸ | NTSR1 | P30989 | 10/20 | 0.55 |
| ▸ | NTSR2 | O95665 | 8/20 | 0.55 |
| ▸ | SORT1 | Q99523 | 7/20 | 0.55 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.54 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.54 |
| ▸ | APLNR | P35414 | 1/20 | 0.52 |
| ▸ | NPY1R | P25929 | 1/20 | 0.52 |
| ▸ | NPY2R | P49146 | 1/20 | 0.52 |
| ▸ | NPY4R | P50391 | 1/20 | 0.52 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29429586 | 0.97 | NTSR1 (0.56) | C5AR1EPHA2NTSR1NTSR2SORT1 | |
| SCHEMBL29634905 | 0.95 | AGTR1 (0.56) | C5AR1EPHA2NTSR1NTSR2SORT1 | |
| SCHEMBL30082469 | 0.94 | C5AR1 (0.54) | C5AR1EPHA2NTSR1NTSR2SORT1 | |
| SCHEMBL29973760 | 0.93 | AGTR2 (0.63) | C5AR1EPHA2NTSR1NTSR2SORT1 | |
| SCHEMBL29701256 | 0.91 | AGTR2 (0.65) | C5AR1EPHA2NTSR1NTSR2SORT1 | |
| SCHEMBL29416004 | 0.90 | NPY2R (0.59) | NPY1RNPY2RNPY4RNPY5R | |
| SCHEMBL29701260 | 0.90 | C5AR1 (0.60) | C5AR1NTSR1NTSR2SORT1AGTR1 | |
| SCHEMBL9010599 | 0.90 | AGTR1 (0.62) | C5AR1NTSR1NTSR2SORT1AGTR1 | |
| SCHEMBL9010604 | 0.90 | AGTR1 (0.62) | C5AR1NTSR1NTSR2SORT1AGTR1 | |
| SCHEMBL29649735 | 0.90 | AGTR1 (0.62) | C5AR1NTSR1NTSR2SORT1AGTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4096697-A1 | PEPTIDES USEFUL IN PRESERVATION AND/OR RESTORATION OF FUNCTIONAL PANCREATIC ISLETS AND IN TREATING DIABETES | The National Institute for Biotechnology in the Negev Ltd. (IL) | 2022-12-07 | — | — | EP | disclosed |