Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 5/20 | 0.47 |
| ▸ | FPR3 | P25089 | 1/20 | 0.46 |
| ▸ | FPR2 | P25090 | 1/20 | 0.46 |
| ▸ | PTPN7 | P35236 | 6/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 6/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30116927 | 0.95 | P2RX7 (0.49) | P2RX7FPR3FPR2PTPN7DUSP3 | |
| SCHEMBL30117031 | 0.84 | NAMPT (0.41) | P2RX7EPHX1MEN1POLBKMT2A | |
| SCHEMBL30117022 | 0.81 | MLYCD (0.49) | P2RX7EPHX1MEN1KMT2AHPGD | |
| SCHEMBL26633839 | 0.80 | EPHX1 (0.50) | EPHX1POLBHPGDSMN1; SMN2RAB9A | |
| SCHEMBL30116947 | 0.80 | FPR3 (0.46) | P2RX7FPR3FPR2MEN1POLB | |
| SCHEMBL25205210 | 0.79 | EPHX1 (0.44) | EPHX1MEN1POLBKMT2AHPGD | |
| SCHEMBL30116944 | 0.78 | CYP3A4 (0.47) | FPR3FPR2HTT | |
| SCHEMBL26764320 | 0.78 | EPHX1 (0.68) | EPHX1MEN1POLBKMT2AHPGD | |
| SCHEMBL30116961 | 0.77 | P2RX7 (0.47) | P2RX7FPR3FPR2 | |
| SCHEMBL26099286 | 0.77 | SMN1; SMN2 (0.41) | EPHX1MEN1POLBKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115461327-A | Spiro urea derivatives | 爱杜西亚药品有限公司 | 2022-12-09 | — | — | CN | claimed |
| EP-4584250-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | Biohaven Therapeutics Ltd. (VG) | 2025-07-16 | — | — | EP | disclosed |
| WO-2024054811-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-14 | — | — | WO | disclosed |
| CN-115461327-A | Spiro urea derivatives | 爱杜西亚药品有限公司 | 2022-12-09 | — | — | CN | disclosed |