Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | GFER | P55789 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 7/20 | 0.56 |
| ▸ | ATP4A | P20648 | 2/20 | 0.56 |
| ▸ | ATP4B | P51164 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 6/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.51 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.51 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.51 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28911568 | 1.00 | MEN1 (0.64) | MEN1KMT2AMAPTSMN1; SMN2GFER | |
| SCHEMBL18769586 | 0.83 | MEN1 (0.79) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL25959092 | 0.82 | RAB9A (0.68) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL3604035 | 0.81 | ATP4A (0.56) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL30118266 | 0.81 | MEN1 (0.67) | MEN1KMT2AMAPTSMN1; SMN2GFER | |
| SCHEMBL30294199 | 0.81 | MAPT (0.67) | MEN1KMT2AMAPTSMN1; SMN2GFER | |
| SCHEMBL28960730 | 0.81 | MEN1 (0.67) | MEN1KMT2AMAPTSMN1; SMN2GFER | |
| SCHEMBL28911472 | 0.81 | NPC1 (0.68) | MEN1KMT2AMAPTSMN1; SMN2GFER | |
| SCHEMBL10812660 | 0.81 | ROCK1 (0.62) | MEN1KMT2AMAPTSMN1; SMN2RAB9A | |
| SCHEMBL10923160 | 0.81 | ABL1 (0.61) | MEN1KMT2AMAPTSMN1; SMN2GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115448915-A | SIRT5 inhibitor and preparation method and application thereof | 广西师范大学 | 2022-12-09 | — | — | CN | disclosed |