SCHEMBL30118969

SCHEMBL30118969

Cc1cc(-c2cccc(C(C)(C)C)c2)cc(-n2c3ccccc3c3ccccc32)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 1/20 0.41
RXRA P19793 3/20 0.38
RXRB P28702 3/20 0.38
KDM4E B2RXH2 1/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
OPRD1 P41143 3/20 0.37
PTPN5 P54829 2/20 0.36
OPRM1 P35372 1/20 0.36
OPRK1 P41145 1/20 0.36
PTAFR P25105 1/20 0.34
PPARG P37231 2/20 0.34
PPARA Q07869 1/20 0.34
NOTUM Q6P988 1/20 0.33
ABCG2 Q9UNQ0 1/20 0.33
SERPINE1 P05121 1/20 0.33
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
RXFP1 Q9HBX9 1/20 0.32
TMEM97 Q5BJF2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12353914 0.92 KIF11 (0.45) KIF11RXRARXRBKDM4EATM
SCHEMBL12000707 0.87 KDM4E (0.47) KIF11RXRARXRBKDM4EATM
SCHEMBL4546839 0.86 L3MBTL1 (0.48) KDM4EATML3MBTL1RXFP1ALDH1A1
SCHEMBL12353923 0.85 L3MBTL1 (0.44) KIF11RXRARXRBKDM4EATM
SCHEMBL4546845 0.84 L3MBTL1 (0.47) KDM4EATML3MBTL1OPRD1RXFP1
SCHEMBL25693022 0.84 KDM4E (0.52) KDM4EATML3MBTL1RXFP1ALDH1A1
SCHEMBL12353932 0.83 L3MBTL1 (0.46) KIF11RXRARXRBKDM4EATM
SCHEMBL12000705 0.83 KIF11 (0.49) KIF11RXRARXRBKDM4EATM
SCHEMBL25014416 0.83 L3MBTL1 (0.44) KDM4EATML3MBTL1PPARGRXFP1
SCHEMBL4546816 0.82 L3MBTL1 (0.52) KDM4EATML3MBTL1RXFP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115667330-A Catalyst system and method for producing polyethylene using the same 陶氏环球技术有限责任公司 2023-01-31 CN disclosed