Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | PARL | Q9H300 | 1/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.42 |
| ▸ | FEN1 | P39748 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4413069 | 1.00 | HSD11B1 (0.70) | HSD11B1L3MBTL1ALDH1A1RAB9AKMT2A | |
| SCHEMBL31471935 | 0.91 | HSD11B1 (0.67) | HSD11B1L3MBTL1ALDH1A1MMP2PARL | |
| SCHEMBL4405981 | 0.86 | HSD11B1 (0.69) | HSD11B1L3MBTL1CHRNB2CHRNA4MMP2 | |
| SCHEMBL10231078 | 0.83 | HSD11B1 (0.61) | HSD11B1ALDH1A1KMT2ATSHR | |
| SCHEMBL31471844 | 0.83 | HSD11B1 (0.61) | HSD11B1L3MBTL1KMT2ACHRNB2CHRNA4 | |
| SCHEMBL31471901 | 0.83 | HSD11B1 (0.61) | HSD11B1ALDH1A1KMT2ATSHR | |
| SCHEMBL12786804 | 0.83 | HSD11B1 (1.00) | HSD11B1ALDH1A1 | |
| SCHEMBL12786753 | 0.83 | HSD11B1 (1.00) | HSD11B1ALDH1A1 | |
| SCHEMBL4403548 | 0.83 | HSD11B1 (0.64) | HSD11B1L3MBTL1CHRNB2CHRNA4 | |
| SCHEMBL1618372 | 0.83 | HSD11B1 (0.61) | HSD11B1ALDH1A1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022253309-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS AND APPLICATION THEREOF | 首药控股(北京)股份有限公司 | 2022-12-08 | — | — | WO | disclosed |