Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.67 |
| ▸ | PARL | Q9H300 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 5/20 | 0.44 |
| ▸ | MMP2 | P08253 | 4/20 | 0.44 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.44 |
| ▸ | FEN1 | P39748 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 3/20 | 0.43 |
| ▸ | MMP8 | P22894 | 3/20 | 0.43 |
| ▸ | MMP1 | P03956 | 2/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | MMP14 | P50281 | 1/20 | 0.43 |
| ▸ | MMP16 | P51512 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4413069 | 0.91 | HSD11B1 (0.70) | HSD11B1PARLALDH1A1MMP2ALOX5AP | |
| SCHEMBL30121385 | 0.91 | HSD11B1 (0.70) | HSD11B1PARLALDH1A1MMP2ALOX5AP | |
| SCHEMBL4405981 | 0.84 | HSD11B1 (0.69) | HSD11B1MMP2ALOX5APFEN1MMP3 | |
| SCHEMBL31471901 | 0.81 | HSD11B1 (0.61) | HSD11B1ALDH1A1 | |
| SCHEMBL12786804 | 0.81 | HSD11B1 (1.00) | HSD11B1ALDH1A1GAA | |
| SCHEMBL12786753 | 0.81 | HSD11B1 (1.00) | HSD11B1ALDH1A1GAA | |
| SCHEMBL1618372 | 0.81 | HSD11B1 (0.61) | HSD11B1ALDH1A1 | |
| SCHEMBL4403548 | 0.81 | HSD11B1 (0.64) | HSD11B1GAAMMP3MMP8L3MBTL1 | |
| SCHEMBL10231078 | 0.81 | HSD11B1 (0.61) | HSD11B1ALDH1A1 | |
| SCHEMBL31471931 | 0.80 | HSD11B1 (0.67) | HSD11B1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025100889-A1 | QUINAZOLINE DERIVATIVE, SALT THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT | 한국화학연구원 | 2025-05-15 | — | — | WO | disclosed |