Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 3/20 | 0.48 |
| ▸ | MCOLN3 | Q8TDD5 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10231078 | 1.00 | HSD11B1 (0.61) | HSD11B1LMNAALDH1A1SMN1; SMN2PKM | |
| SCHEMBL1618372 | 1.00 | HSD11B1 (0.61) | HSD11B1LMNAALDH1A1SMN1; SMN2PKM | |
| SCHEMBL566287 | 0.85 | HSD11B1 (0.54) | HSD11B1 | |
| Hydrochloric Acid SCHEMBL567432 | 0.84 | HSD11B1 (0.53) | HSD11B1 | |
| SCHEMBL8692108 | 0.83 | HSD11B1 (0.54) | HSD11B1ALDH1A1MEN1KMT2A | |
| SCHEMBL30121385 | 0.83 | HSD11B1 (0.70) | HSD11B1ALDH1A1TSHRKMT2A | |
| SCHEMBL4413069 | 0.83 | HSD11B1 (0.70) | HSD11B1ALDH1A1TSHRKMT2A | |
| SCHEMBL31471935 | 0.81 | HSD11B1 (0.67) | HSD11B1ALDH1A1 | |
| SCHEMBL4405981 | 0.79 | HSD11B1 (0.69) | HSD11B1PKMMCOLN3 | |
| SCHEMBL31471844 | 0.78 | HSD11B1 (0.61) | HSD11B1MCOLN3AKR1C3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025100889-A1 | QUINAZOLINE DERIVATIVE, SALT THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME AS ACTIVE INGREDIENT | 한국화학연구원 | 2025-05-15 | — | — | WO | disclosed |