Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 7/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3922915 | 1.00 | CCR2 (0.41) | CCR2ADRA1DADRA2AADRA2CADRA1A | |
| SCHEMBL4486953 | 0.85 | ADRA1D (0.48) | CCR2ADRA1DADRA2CADRA1AADRA1B | |
| SCHEMBL15713787 | 0.85 | CCR2 (0.44) | CCR2ADRA1DADRA2AADRA2CADRA1A | |
| Hydrochloric Acid SCHEMBL1262739 | 0.84 | ADRA1D (0.47) | CCR2ADRA1DADRA2CADRA1AADRA1B | |
| SCHEMBL1807106 | 0.81 | CYP2A6 (0.39) | CYP2A6F2ALDH1A1L3MBTL1 | |
| SCHEMBL1139918 | 0.81 | CCR2 (0.41) | CCR2ADRA1DADRA2AADRA2CADRA1A | |
| SCHEMBL16616435 | 0.81 | PSEN1 (0.47) | CCR2 | |
| SCHEMBL30122107 | 0.81 | CCR2 (0.41) | CCR2ADRA1DADRA2AADRA2CADRA1A | |
| SCHEMBL13873006 | 0.80 | CCR2 (0.41) | CCR2ADRA1DADRA2AADRA2CADRA1A | |
| SCHEMBL14492056 | 0.79 | L3MBTL1 (0.40) | ADRA1DADRA2AADRA2CADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115572252-B | Isoindolinone inhibitors of MDM2-P53 interaction with anticancer activity | 阿斯泰克斯治疗有限公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-115572252-A | Isoindolinone inhibitors of MDM2-P53 interaction with anti-cancer activity | 阿斯泰克斯治疗有限公司 | 2023-01-06 | — | — | CN | disclosed |