Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 11/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.38 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.33 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29185705 | 0.74 | KDM4E (0.42) | KLKB1ALDH1A1KDM4EKMT2A | |
| SCHEMBL28132529 | 0.74 | ALDH1A1 (0.38) | L3MBTL1ALDH1A1KDM4EKMT2A | |
| SCHEMBL2900590 | 0.73 | KDM4E (0.35) | KLKB1ALDH1A1KDM4EKMT2AENPP3 | |
| SCHEMBL2187316 | 0.72 | — | — | |
| SCHEMBL17066899 | 0.72 | NPC1 (0.44) | L3MBTL1ALDH1A1KDM4ETSHRKMT2A | |
| SCHEMBL2186778 | 0.72 | KDM4E (0.30) | ALDH1A1KDM4E | |
| SCHEMBL20477442 | 0.68 | NPC1 (0.47) | CA5AL3MBTL1ALDH1A1KDM4EPOLB | |
| SCHEMBL21818557 | 0.68 | ACHE (0.39) | — | |
| SCHEMBL2161366 | 0.68 | KLKB1 (0.40) | KLKB1ALDH1A1KDM4EKMT2A | |
| SCHEMBL24211047 | 0.68 | KLKB1 (0.35) | KLKB1L3MBTL1ALDH1A1KMT2ARIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022258052-A1 | HETEROCYCLIC LACTAM COMPOUND, AND PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | 劲方医药科技(上海)有限公司 | 2022-12-15 | — | — | WO | disclosed |