Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 4/20 | 0.49 |
| ▸ | DRD3 | P35462 | 3/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28168044 | 0.84 | CYP2C9 (0.68) | CYP2D6DRD2DRD3HTR2AKDM4E | |
| SCHEMBL10267443 | 0.79 | CYP2D6 (0.77) | CYP2D6KDM4EALDH1A1HTTMEN1 | |
| SCHEMBL27637811 | 0.73 | LMNA (0.52) | DRD2HTR2AKDM4EALDH1A1MEN1 | |
| SCHEMBL1288198 | 0.72 | CYP2D6 (1.00) | CYP2D6HTTKCNH2CYP2C9 | |
| SCHEMBL1287941 | 0.72 | CYP2D6 (1.00) | CYP2D6HTTKCNH2CYP2C9 | |
| SCHEMBL6436835 | 0.72 | CYP2D6 (1.00) | CYP2D6HTTKCNH2CYP2C9 | |
| SCHEMBL1688350 | 0.71 | CYP2D6 (0.82) | CYP2D6ALDH1A1KCNH2CYP2C9 | |
| SCHEMBL27618693 | 0.69 | MEN1 (0.46) | DRD2DRD3HTR2AKDM4EALDH1A1 | |
| SCHEMBL25249413 | 0.69 | CCNT1 (0.49) | HTR2A | |
| SCHEMBL30566002 | 0.69 | CCNT1 (0.49) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230310573-A1 | Stabilized Vaccine Compositions | JANSSEN VACCINES AND PREVENTION B.V. (NL) | 2023-10-05 | — | — | US | disclosed |
| EP-4126023-A1 | STABILIZED VACCINE COMPOSITIONS | Janssen Vaccines & Prevention B.V. (NL) | 2023-02-08 | — | — | EP | disclosed |