Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 5/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.43 |
| ▸ | CHRNA9 | Q9UGM1 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30124750 | 0.85 | CYP1A2 (0.58) | PARP14PARP10PARP1KMT2AMEN1 | |
| SCHEMBL30124974 | 0.82 | ALDH1A1 (0.48) | CASP6GFERKMT2APOLBMEN1 | |
| SCHEMBL30124760 | 0.81 | NAMPT (0.47) | CASP6GFERKMT2APOLBMEN1 | |
| SCHEMBL23928600 | 0.80 | MAPT (0.43) | CASP6GFERKMT2ALMNAPOLB | |
| SCHEMBL4985313 | 0.79 | GFER (0.70) | PARP14PARP10CASP6GFERKMT2A | |
| SCHEMBL3276407 | 0.74 | MEN1 (0.74) | PARP14PARP10KMT2ALMNAPOLB | |
| SCHEMBL7258616 | 0.74 | CASP6 (0.53) | PARP14PARP10PARP1CASP6GFER | |
| SCHEMBL23928559 | 0.73 | MAPT (0.43) | KMT2ALMNAPOLBMEN1ALDH1A1 | |
| SCHEMBL23928587 | 0.72 | NPSR1 (0.60) | KMT2ALMNAMEN1ALDH1A1MAPT | |
| SCHEMBL30125096 | 0.71 | NAMPT (0.57) | PARP14PARP10PARP1GFERKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11548875-B2 | Inhibitor compounds for male contraception | UNIVERSITY OF WASHINGTON (US) | 2023-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11548875-B2 | Inhibitor compounds for male contraception | ALDH1A1, ALDH3A1, ALDH16A1 | PARP14 880/4885PARP10 1073/4885PARP1 592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.