Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.47 |
| ▸ | HPGDS | O60760 | 2/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | PROKR1 | Q8TCW9 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30127280 | 0.95 | PDE4B (0.52) | PDE4BPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL30126593 | 0.91 | PIK3CD (0.44) | PDE4BPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL30127359 | 0.89 | PDE4B (0.48) | PDE4BPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL30127386 | 0.84 | HPGDS (0.45) | PDE4BPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL30126000 | 0.84 | PDE4B (0.53) | PDE4BPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL30125786 | 0.82 | PIK3CD (0.48) | PDE4BPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL30125952 | 0.82 | PIK3CD (0.48) | PDE4BPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL30127558 | 0.82 | PIK3CD (0.48) | PDE4BPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL30126934 | 0.82 | PIK3CD (0.48) | PDE4BPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL30126933 | 0.79 | PIK3CD (0.44) | PDE4BPIK3CDPIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022266458-A1 | 6-HETEROCYCLOALKYL-QUINAZOLINE DERIVATIVES AND USES THEREOF | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2022-12-22 | — | — | WO | disclosed |