Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.52 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.49 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.49 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | HPGDS | O60760 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.41 |
| ▸ | CCNK | O75909 | 1/20 | 0.41 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30125994 | 0.95 | PDE4B (0.47) | PDE4BPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL30126593 | 0.92 | PIK3CD (0.44) | PDE4BPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL30126000 | 0.89 | PDE4B (0.53) | PDE4BPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL30127359 | 0.84 | PDE4B (0.48) | PDE4BPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL30125750 | 0.82 | PIK3CD (0.51) | PDE4BPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL30125883 | 0.82 | PIK3CD (0.51) | PDE4BPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL30126517 | 0.82 | PIK3CD (0.51) | PDE4BPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL30127389 | 0.82 | PIK3CD (0.51) | PDE4BPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL31017634 | 0.81 | PDE4B (0.50) | PDE4BHPGDSTP53MAPTLMNA | |
| SCHEMBL25831131 | 0.81 | PDE4B (0.50) | PDE4BHPGDSTP53MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022266458-A1 | 6-HETEROCYCLOALKYL-QUINAZOLINE DERIVATIVES AND USES THEREOF | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2022-12-22 | — | — | WO | disclosed |