Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.36 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | KLK7 | P49862 | 4/20 | 0.34 |
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | IL6ST | P40189 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
| ▸ | USP19 | O94966 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | Q9HBH1 | 1/20 | 0.31 | |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3021447 | 1.00 | PPARA (0.37) | PPARAPLA2G10PLA2G5CSNK2BCSNK2A1 | |
| SCHEMBL3021441 | 1.00 | PPARA (0.37) | PPARAPLA2G10PLA2G5CSNK2BCSNK2A1 | |
| SCHEMBL13904727 | 0.93 | PPARA (0.40) | PPARAPLA2G10PLA2G5KLK7KLK5 | |
| SCHEMBL3006140 | 0.91 | PPARA (0.39) | PPARAPLA2G10PLA2G5KLK7KLK5 | |
| SCHEMBL3006139 | 0.91 | PPARA (0.39) | PPARAPLA2G10PLA2G5KLK7KLK5 | |
| SCHEMBL16498239 | 0.91 | PPARA (0.39) | PPARAPLA2G10PLA2G5KLK7KLK5 | |
| SCHEMBL28948933 | 0.91 | PPARA (0.39) | PPARAPLA2G10PLA2G5KLK7KLK5 | |
| SCHEMBL28948936 | 0.91 | PPARA (0.39) | PPARAPLA2G10PLA2G5KLK7KLK5 | |
| SCHEMBL28948939 | 0.91 | PPARA (0.39) | PPARAPLA2G10PLA2G5KLK7KLK5 | |
| SCHEMBL3020667 | 0.88 | PPARA (0.39) | PPARACSNK2BCSNK2A1FAAHIL6ST |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100204200-A1 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2010-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204200-A1 | INHIBITORS OF CATHEPSIN S | CTSS, CTSE, CTSV | PPARA 2508/4885PLA2G10 956/4885PLA2G5 391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.