Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SLC16A3 | O15427 | 4/20 | 0.36 |
| ▸ | SLC16A1 | P53985 | 4/20 | 0.36 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.35 |
| ▸ | GLS | O94925 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | GRN | P28799 | 1/20 | 0.33 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2833994 | 0.89 | HTR2C (0.52) | HTR2CSLC6A4HTR2ASLC16A3SLC16A1 | |
| SCHEMBL2838918 | 0.86 | NPSR1 (0.37) | SLC16A3SLC16A1ALDH1A1MEN1TSHR | |
| SCHEMBL3012801 | 0.79 | ALDH1A1 (0.34) | SLC16A3SLC16A1MCTS1ALDH1A1MEN1 | |
| SCHEMBL2837803 | 0.77 | HTR2C (0.52) | HTR2CSLC6A4SLC16A3SLC16A1MCTS1 | |
| SCHEMBL2836798 | 0.76 | MEN1 (0.39) | HTR2CSLC6A4HTR2AALDH1A1MEN1 | |
| SCHEMBL2838922 | 0.74 | ALDH1A1 (0.43) | ALDH1A1MEN1TSHRKMT2ANPSR1 | |
| SCHEMBL3012796 | 0.73 | RIPK1 (0.38) | ALDH1A1 | |
| SCHEMBL2838656 | 0.73 | ALDH1A1 (0.39) | SLC16A3SLC16A1ALDH1A1TSHRKMT2A | |
| SCHEMBL10080842 | 0.70 | HTR2C (0.67) | HTR2CSLC6A4HTR2ASLC16A3SLC16A1 | |
| SCHEMBL14924172 | 0.70 | HTR2C (0.72) | HTR2CSLC6A4HTR2ASLC16A3SLC16A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8334301-B2 | 5-Membered heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-12-18 | — | — | US | disclosed |
| US-20100210696-A1 | 5-MEMBERED HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100210696-A1 | 5-MEMBERED HETEROCYCLIC COMPOUND | NPY4R, NPY5R, NPY1R | HTR2C 1425/4885SLC6A4 1108/4885HTR2A 3226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.