Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | LPL | P06858 | 1/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
| ▸ | DBH | P09172 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 2/20 | 0.31 |
| ▸ | BTK | Q06187 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20576307 | 1.00 | EGFR (0.34) | EGFRLPLLIPGDBHJAK2 | |
| SCHEMBL20577299 | 0.84 | EGFR (0.34) | EGFRDBHJAK2BTK | |
| SCHEMBL20577340 | 0.83 | LPL (0.34) | LPLLIPGJAK2BTK | |
| SCHEMBL20577313 | 0.82 | JAK2 (0.37) | LPLLIPGJAK2BTK | |
| SCHEMBL26145480 | 0.82 | UCHL1 (0.32) | — | |
| SCHEMBL21725713 | 0.81 | TNF (0.37) | EGFRLPLLIPGJAK2BTK | |
| SCHEMBL12005673 | 0.80 | LPL (0.36) | EGFRLPLLIPGJAK2BTK | |
| SCHEMBL21725879 | 0.79 | PIM3 (0.37) | EGFRJAK2BTK | |
| SCHEMBL20577587 | 0.78 | EGFR (0.33) | EGFR | |
| SCHEMBL31481849 | 0.78 | NR3C1 (0.35) | LPLLIPGJAK2BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111032658-B | 5-5 fused rings as C5a inhibitors | 凯莫森特里克斯股份有限公司 | 2022-12-20 | — | — | CN | disclosed |