8-Hydroxy Quinaldine

8-Hydroxy Quinaldine

SCHEMBL30128554

Cc1ccc2cccc(O)c2n1.Cc1ccc2cccc(O)c2n1.Oc1ccccc1.Oc1ccccc1.[Al]

nearest known ligand 0.79

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 2/20 0.79
KMT2A Q03164 5/20 0.49
KDM4E B2RXH2 3/20 0.49
PLAU P00749 1/20 0.49
NCF1 P14598 1/20 0.49
ALOX12 P18054 2/20 0.47
ALDH1A1 P00352 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2C9 P11712 1/20 0.47
HPGD P15428 1/20 0.47
CYP2C19 P33261 1/20 0.47
HIF1A Q16665 1/20 0.47
HSD17B10 Q99714 1/20 0.47
RAB9A P51151 2/20 0.47
CCR1 P32246 1/20 0.47
CCR5 P51681 1/20 0.47
CD74 P04233 1/20 0.46
MIF P14174 1/20 0.46
PARP1 P09874 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
8-Hydroxy Quinaldine SCHEMBL625310 1.00 METAP2 (0.79) METAP2KMT2AKDM4EPLAUNCF1
8-Hydroxy Quinaldine SCHEMBL8634752 1.00 METAP2 (0.79) METAP2KMT2AKDM4EPLAUNCF1
8-Hydroxy Quinaldine SCHEMBL3265166 0.98 METAP2 (0.82) METAP2KMT2AKDM4EPLAUNCF1
8-Hydroxy Quinaldine SCHEMBL4386958 0.97 METAP2 (0.79) METAP2KMT2AKDM4EPLAUNCF1
8-Hydroxy Quinaldine SCHEMBL19640292 0.97 METAP2 (0.79) METAP2KMT2AKDM4EPLAUNCF1
8-Hydroxy Quinaldine SCHEMBL19327239 0.97 METAP2 (0.79) METAP2KMT2AKDM4EPLAUNCF1
8-Hydroxy Quinaldine SCHEMBL5089361 0.91 METAP2 (0.96) METAP2KMT2AKDM4EPLAUNCF1
8-Hydroxy Quinaldine SCHEMBL30295552 0.91 METAP2 (0.96) METAP2KMT2AKDM4EPLAUNCF1
8-Hydroxy Quinaldine SCHEMBL546577 0.91 METAP2 (0.96) METAP2KMT2AKDM4EPLAUNCF1
8-Hydroxy Quinaldine SCHEMBL262742 0.91 METAP2 (0.96) METAP2KMT2AKDM4EPLAUNCF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115477586-A Novel compound and organic light emitting device comprising the same 东进世美肯株式会社 2022-12-16 CN disclosed